学术报告
题目：Signaling dynamics in cell differentiation and tissue maintenance
报告人：Jian Lu, Ph.D.
The laboratory of Dr. Andrew G. Clark at the Department of Molecular Biology and Genetics, Cornell University.
时间：Thursday 3:30 p.m., May 31
地点：生命科学学院411会议室
MicroRNAs are small non-coding RNAs that regulate expression of target genes at the post-transcriptional level. A microRNA can target more than 100 genes and one gene can in turn be regulated by multiple microRNAs. Given the broad interactions between microRNAs and their targets, the origin and evolution of such a system is intriguing. In my seminar, I will first illustrate the birth and death process of microRNAs by showing that most newly emerged microRNAs are evolutionarily transient. Next I will talk about genetic variation in miRNA regulatory networks as revealed by the 1000 Genomes Project and the implication of miRNA regulation on human evolution. Finally I will present experimental evidences of miRNA canalization effects against environmental perturbations.
欢迎各位老师和同学积极参加！