学术报告
题目：Maximizing the utility of TCGA genomic data: Tools, Analysis and Discovery
报告人：Han Liang, Ph.D.
Assistant Professor, Department of Bioinformatics and Computational Biology
The University of Texas MD Anderson Cancer
时间：2014年6月17日（周二）上午9:30 AM
地点：新生物楼311室
The Cancer Genome Atlas (TCGA) project represents the largest effort to systematically characterize the molecular profiles of human cancers. A central question for the cancer research community is how to use these genomic and proteomic data to guide cancer care. In my talk, I will first introduce two useful bioinformatics tools we recently developed for effectively analyzing and visualizing TCGA data: SurvNet and TCPA. Then I will present a systematic evaluation of the power of diverse TCGA molecular data with or without clinical variables in predicting patient survival and discuss the potential utility of cross-tumor analysis. To facilitate community efforts to make prognostic modeling transparent and reproducible, we established an open-access model evaluation platform. Finally, I will focus on the biomedical significance and clinical relevance of expressed pseudogenes in human cancer.
Bio
Dr. Han Liang received his B.S in chemistry from Peking University. In 2006, he received Ph.D. from Princeton University through the Quantitative and Computational Biology program. As a postdoctoral researcher, he worked with Dr. Wen-Hsiung Li, a world-class human geneticist, on non-coding RNAs and evolutionary genomics at the University of Chicago. Since he joined MD Anderson Cancer Center in 2009, he has led a vigorous research group that focuses on the development of computational and systems-biology approaches to analyzing high-throughput cancer genomic data and identifying driver molecular events. He is the PI for multiple NIH grants. Since 2005, he has published 48 papers including 30 as first or corresponding author. In the last two years, he authored 13 papers in Nature, Cell or Nature sister journals, including corresponding-author papers in Nature Biotechnology, Nature Methods, Nature Communications and Genome Research. He is one young leader in the research community of cancer genomics such as The Cancer Genome Atlas and International Cancer Genome Consortium.
欢迎各位老师和同学积极参加！