学术报告
题目：Genetic Dissection of Neural Circuits in Brain Disorders
报告人：Xiangdong William Yang (杨向东)
Professor, Center for Neurobehavioral Genetics,
Semel Institute for Neuroscience & Human Behavior,
Department of Psychiatry & Biobehavioral Sciences, Brain Research Institute,
David Geffen School of Medicine, University of California at Los Angeles
时间：2012年11月16日（周五），10:00-11:00 AM
地点：生命科学学院208会议室
Dr. Xiangdong William Yang is a professor in the Department of Psychiatry & Biobehavioral Sciences and a member of the Center for Neurobehavioral Genetics at the Semel Institute of the University of California at Los Angeles (UCLA). Xiangdong was a biochemistry student at Peking University from 1985-1987, prior to transferring to Yale University. He obtained combined B.S./M.S. degrees from the Department of Molecular Biophysics & Biochemistry at Yale in 1991. He completed M.D./Ph.D. training at Rockefeller University (Ph.D., 1998) and Weill Medical College of Cornell University (M.D., 2000). During his Ph.D. thesis research under the mentorship of Dr. Nathaniel Heintz at Rockefeller University, Dr. Yang co-invented (with Nathaniel Heintz and Peter Model) a powerful mouse genetic technology to engineer Bacterial Artificial Chromosomes (BACs) and to generate BAC transgenic mice. Dr. Yang`s own laboratory, established at UCLA in 2002, has made significant contributions in the use of BAC transgenesis to model human neurodegenerative disorders including Huntington`s disease (HD), Huntington`s Disease Like 2 (HDL2) and Parkinson`s disease (PD), and the use of such models to dissect disease mechanisms and identify therapeutic targets. The Yang lab has also developed novel tools to study neuronal cell-type-specific gene expression, and to decipher in vivo protein interaction networks. Finally, the Yang lab studies the role of basal ganglia circuitry in the generation of normal and pathological behaviors. Dr. Yang is a recipient of Brain Disorder Award from the McKnight Foundation, the Carol Moss Spivak Scholar Award from UCLA Brain Research Institute, and serves on the scientific advisory board for the Hereditary Disease Foundation.
联系人：张研（电话：62754880）
欢迎各位老师和同学积极参加！
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