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Nonlinear Dynamics and Stochasticity of Core Genetic Regulation of Competence in Wild-type Bacillus subtilis and in Evolutionary Plausible Mutants

日期: 2012-10-19

学术报告
题目:Nonlinear Dynamics and Stochasticity of Core Genetic Regulation of Competence in Wild-type Bacillus subtilis and in Evolutionary Plausible Mutants
报告人: Prof. Marc Turcotte (Department of Mathematics, The University of Texas at Arlington)
报告时间:2012年10月23日(星期二)下午13:00
报告地点:北京大学定量生物学中心(原理论生物学中心)老化学楼东配楼102会议室(理教路西/老光华楼北侧)
摘要:
In the first part of the talk, I will be explaining how the subtle interplay of non-linear dynamics and stochasticicity pervades the phenotype of competence in wild-type bacterium Bacillus subtilis. In the second part of the talk, I will be focusing on the behavior of evolutionary plausible mutant(s) we recently studied. I will show how nonlinear dynamics and stochasticity collaborate closely to implement phenotype, and how the topology of the core regulatory circuit correlates well to experimentally measurable observables.
This talk should be of interest to applied mathematicians, physicists, or bioengineers interested in biology, particularly in the topic of core genetic regulation. It should also be of equal interest to quantitative biologists interested in mathematical modeling and predictions.
欢迎大家参加!