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学术报告
题目:Understanding tumor cell maneuvers with MADM
报告人:Hui Zong, PhD
Assistant Professor, Institute of Molecular Biology, University of Oregon,
时间:2012年9月12日(周三),14:00-15:00 PM
地点:生命学院208会议室
Zong lab utilizes a powerful mouse genetic system termed MADM (Mosaic Analysis with Double Markers), which creates sporadic GFP-labeled tumor suppressor mutant cells that are traceable during the entire course of tumorigenesis. Dr. Zong will discuss how their high-resolution modeling of two types of brain tumors (glioma and medulloblastoma) provided mind-opening insights into the swift maneuvers of tumor cells.
Selected Publications:
1. Liu, C., Sage, J.C., Miller, M.R., Verhaak, R.G.W., Hippenmeyer, S., Vogel, H., Foreman,O., Bronson, R.T., Nishiyama, A., Luo, L., Zong, H (2011). Mosaic Analysis with Double Markers Reveals Tumor Cell-of-Origin in Glioma. Cell, 146 (2), 209-221.
2. Muzumdar, M., Luo, L., & Zong, H (2007). Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM). Proc Natl Acad Sci USA 104 (11), 4495-4500.
3. Zong, H., Espinosa, J.S., Su, H.H., Muzumdar, M.D., & Luo, L. (2005) Mosaic analysis with double markers in mice. Cell 121 (3), 479-492.
联系人:刘东(电话:62753189)
欢迎各位老师和同学积极参加!