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Coordination of Cell Signaling and Membrane Trafficking in Metabolic Control

日期: 2012-09-11

学术报告
题目:Coordination of Cell Signaling and Membrane Trafficking in Metabolic Control
报告人:Xiaowei Chen
Howard Hughes Medical Institute and University of Michigan
时间: Thursday 10:30 a.m., September 20
地点:生命学院610室
Metabolic disorders have become a worldwide epidemic that increasingly threatens human health, causing conditions including type 2 diabetes, cardiovascular diseases, and certain types of cancer. These diseases

often result from dysfunction in glucose and lipid metabolism. My research concerns insulin-stimulated glucose transport and cholesterol homeostasis, both of which rely on faithful membrane trafficking programs governed by cellular signaling. I will present work that leads to: (1) delineation of a novel signaling pathway that regulates the trafficking of insulin-responsive glucose transporter Glut4, (2) discovery of a novel gene critical for cholesterol homeostasis during in vivo studies of ER-Golgi trafficking.
欢迎各位老师和同学积极参加!