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Massively parallel interrogation of human functional variants modulating cancer immunosurveillance
Crop root bacterial and viral genomes reveal unexplored species and microbiome patterns
3D genome landscape of primary and metastatic colorectal carcinoma reveals the regulatory mechanism of tumorigenic and metastatic gene expression
CTDP1 and RPB7 stabilize Pol II and permit reinitiation
The mechanisms governing the termination and subsequent reinitiation of RNA polymerase II (Pol II) remain poorly understood. Here we find that depletion of RPB7 leads to the destabilization of Pol II’s largest subunit, RPB1.
