Self-inactivating AAV-CRISPR at different ages enables sustained amelioration of Huntington’s disease deficits in BAC226Q mice
Mar. 24, 2026
Decoding disease-relevant variants with base and prime editors at scale
Mar. 24, 2026
A genetically encoded fluorescent sensor for monitoring spatiotemporal prostaglandin E2 dynamics in vivo
Mar. 16, 2026
Grass inflorescence morphodynamics guides yield improvement in wheat
Mar. 13, 2026
Heterochronic parabiosis alters the transcriptomic landscape to combat aging and aging-related diseases in aging-accelerated mice
Mar. 09, 2026
Enalapril mitigates senescence and aging-related phenotypes in human cells and mice via pSmad1/5/9-driven antioxidative genes
Mar. 09, 2026
A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse
Mar. 09, 2026
Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs
Mar. 05, 2026
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis
Feb. 26, 2026
Complement C3 recognition by C3 convertases
Feb. 21, 2026