第八届中国化学会-英国皇家学会青年化学奖,2022
茅以升北京青年科技奖,2022
中源协和生命医学奖创新突破奖,2022
国家自然科学基金委杰出青年科学基金项目,2018
科技部中青年科技创新领军人才,2018
OKeanos-CAPA Young Investigator Award,2018
Bayer Investigator Award at PKU,2018
中国化学会化学生物学奖突出贡献奖(35周岁以下),2018
第十六届霍英东青年教师基金,2018
第十届“药明康德生命化学研究奖”学者奖,2016
中国化学会青年化学奖,2016
国家自然科学基金委优秀青年科学基金项目,2015
IUPAC Prize for Young Chemists, 2011
2017 - present, the Chinese Cell Biology Society
2013 – present, the RNA society
2013 – present, the Chinese Society of Biochemistry and Molecular Biology
2012 – present, the Chinese Crystallographic Society
2012 – present, the Chinese Chemical Society
1. Song J, Dong L, Sun H, Luo N, Huang Q, Li K, Shen X, Jiang Z, Lv Z, Peng L, Zhang M, Wang K, Liu K, Hong J, Yi C. CRISPR-free, programmable RNA pseudouridylation to suppress premature termination codons. Mol Cell. 2023, 83, 139-155.
2. Liu C, Sun H, Yi Y, Shen W, Li K, Xiao Y, Li F, Li Y, Hou Y, Lu B, Liu W, Meng H, Peng J, Yi C *, Wang J.* Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI. Nat Biotechnol. 2023,41,355-366.
3. Zhang M, Jiang Z, Ma Y, Liu W, Zhuang Y, Lu B, Li K, Peng J, Yi C*. Quantitative profiling of pseudouridylation landscape in the human transcriptome. Nat Chem Biol. 2023 Mar 30. doi: 10.1038/s41589-023-01304-7.
4. Lei Z, Meng H, Liu L, Zhao H, Rao X, Yan Y, Wu H, Liu M, He A,Yi, C*. Mitochondrial base editor induces substantial nuclear off-target mutations. Nature. 2022,606, 804–811
5. Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D., Luan C, Zhang S., Wu H., Gao H, Bai S, Li C, Ding R, Xue N, Lei Z, Chen Y, Guan Y, Siwko S, Cheng Y, Song G, Wang L, Yi C*, Liu M*, Li D* Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing. Nat Biotechnol. 2022, Nov 10. doi: 10.1038/s41587-022-01532-7
6. Zhuang Y, Liu J, Wu H, Zhu Q, Yan Y, Meng H, Chen PR, Yi C*. Increasing the efficiency and precision of prime editing with guide RNA pairs. Nat Chem Biol. 2022; 18:29-37.
7. Lei Z, Meng H, Lv Z, Liu M, Zhao H, Wu H, Zhang X, Liu L, Zhuang Y, Yin K, Yan Y, Yi C.* Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors. Nat Methods. 2021; 18:643-651.
8. Cui Q, Yin K, Zhang X, Ye P, Chen X, Chao J, Meng H, Wei J, Roeth D, Li L, Qin Y, Sun G, Zhang M, Klein J, Huynhle M, Wang C, Zhang L, Badie B, Kalkum M, He C, Yi C* and Shi Y*. Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis. Nat Cancer.2021; 2:932–949.
9. Liu J, Li K, Cai J, Zhang M, Zhang X, Xiong X, Meng H, Xu X, Huang Z, Peng J. Fan J*, YI C*. Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues. Mol Cell. 2020; 77:426-440.
10. Song J, Zhuang Y, Zhu C, Meng H, Lu B, Xie B, Peng J, Li M*, Yi C*. Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation. Nat Chem Biol. 2020; 16: 160-169.