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下载Firefox生命学院学术报告
Title: Combatting ER stress-related diseases by modulating the unfolded protein response
报告人:Likun Wang, PhD
Associate Specialist in Department of Medicine, UCSF
时间:2016年3月24日1:30-2:30
地点:新生物楼411
Abstract: The unfolded protein response (UPR) is an evolutionarily conserved intracellular signaling pathway triggered when unfolded proteins accumulate in the endoplasmic reticulum (ER) to cause “ER stress”. While the UPR initially serves to maintain ER homeostasis, aberrant UPR contributes to cell degenerative disorders and the inappropriate survival of secretory cell tumors. I will talk about our study on how the UPR leads to programmed cell death, and our attempts at harnessing the UPR to combat related diseases.
欢迎各位老师同学积极参加!