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The Neural Mechanism of Empathy
May.13.2018Speaker:Daisong Pan (潘岱松) Chuheng Zhang (张楚珩) Yusen Zhu (朱宇森)
Abstract:
Empathy is not only found in Human sapiens. There are different levels of empathy found in primate or even other vertebrates. As a complex social behavior, it triggers researches on different levels, e.g. psychological level, evolution level, neurocircuit level, and molecular and cellular level. Based on the current researches, people still have debates on the fundamental mechanism of empathy. In our JC, we will start by discussing the definition of empathy and its psychology perspective. Then the brain region that involved in the process, the neuropeptide oxytocin, Norepinephrine and P2X3 receptor will be talked about respectively.
Guest information:
1. Dr. Jun Chen (FMMU)
https://www.fmmu.edu.cn/info/1061/1010.htm
Recommend Literatures:
Review:
1. de Waal, Frans BM, and Stephanie D. Preston. "Mammalian empathy: behavioural manifestations and neural basis." Nature Reviews Neuroscience 18.8 (2017): 498.
Link: https://www.nature.com/articles/nrn.2017.72
Papers:
1. Cox, Christine L., et al. "The balance between feeling and knowing: affective and cognitive empathy are reflected in the brain's intrinsic functional dynamics." Social cognitive and affective neuroscience 7.6 (2011): 727-737.
Link: https://academic.oup.com/scan/article/7/6/727/1645655
2. Lü, Yun-Fei, et al. "The Locus Coeruleus–Norepinephrine System Mediates Empathy for Pain through Selective Up-Regulation of P2X3 Receptor in Dorsal Root Ganglia in Rats." Frontiers in neural circuits 11 (2017): 66.
Link: https://www.frontiersin.org/articles/10.3389/fncir.2017.00066/full
3. Hurlemann, René, et al. "Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans." Journal of Neuroscience 30.14 (2010): 4999-5007.
Link: http://www.jneurosci.org/content/30/14/4999.short